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Archives AB 12.69

Harvard Medical School. Committee on Pernicious Anemia. Records, 1927-1946 (inclusive), 1927-1929 (bulk): Finding Aid

Center for the History of Medicine (Francis A. Countway Library of Medicine)

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Center for the History of Medicine (Francis A. Countway Library of Medicine)

© President and Fellows of Harvard College


Processing of the Harvard Medical School Committee on Pernicious Anemia records was funded by the Francis A. Countway Library of Medicine's Charles S. Minot Fund for Hematology.

Descriptive Summary

Call No.: Archives AB 12.69
Repository: Center for the History of Medicine (Francis A. Countway Library of Medicine)
Creator: Harvard Medical School. Committee on Pernicious Anemia.
Title: Harvard Medical School. Committee on Pernicious Anemia records,
Date(s): 1927-1946 (inclusive),
Date(s): 1927-1929 (bulk).
Quantity: .66 cubic feet ( (1 records center carton).)
Language of materials: Records are in English.
Abstract: The Harvard Medical School Committee on Pernicious Anemia records, 1927-1946 (inclusive), 1927-1929 (bulk), are a product of the committee's administrative activities between 1927 and 1929, during the period of its work toward developing a commercially available liver extract product for the treatment of pernicious anemia.

Processing Information:

Processed by Amber LaFountain, 2012 November.
Processing staff in the Center for the History of Medicine analyzed and described the records, and created a finding aid to improve access. Items were rehoused and, where necessary, photocopied to acid-free paper. Folder titles were transcribed from the originals when available; titles supplied by the processing staff appear in brackets only on the physical folders.

Conditions Governing Access:

Access requires advance notice. Contact Public Services for further information.

Conditions Governing Use:

The Harvard Medical Library does not hold copyright on all the materials in the collection. Requests for permission to publish material from the collection should be directed to Public Services. Researchers who obtain permission to publish from Public Services are responsible for identifying and contacting the persons or organizations that hold copyright.

Preferred Citation:

Harvard Medical School. Committee on Pernicious Anemia. Records, 1927-1946 (inclusive), 1927-1929 (bulk). Harvard Medical Library, Francis A. Countway Library of Medicine, Boston, Mass.

Related Papers in the Francis A. Countway Library of Medicine, Center for the History of Medicine

Historical Notes

The Harvard Medical School Committee on Pernicious Anemia was established in 1927 under the direction of Walter B. Cannon (1871-1945), Professor of Physiology, to oversee the creation of a commercially available liver extract product for the treatment of pernicious anemia. Cannon was joined in the committee by George R. Minot (1885-1950), Assistant Professor of Medicine, Edwin J. Cohn (1892-1953), from the Department of Physical Chemistry, and William B. Castle (1897-1990), of Harvard Medical School's Thorndike Memorial Laboratory at Boston City Hospital, Massachusetts. The committee chose Eli Lilly and Company as the extract's commercial producer, and over the course of two years the committee worked closely with the company and its research director, George H. A. Clowes (1877-1958), to establish the liver extract's potency. The committee consulted with test clinics and laboratories in the United States, Canada, and England during the product's development. In 1928, the liver extract treatment was released to the public, and the committee was disbanded shortly thereafter.

Arrangement

Papers have been maintained in their original arrangement.

Scope and Content

The Harvard Medical School Committee on Pernicious Anemia records, 1927-1946 (inclusive), 1927-1929 (bulk), are a product of the committee's administrative activities between 1927 and 1929, during the period of its work toward developing a commercially available liver extract product for the treatment of pernicious anemia. The bulk of the records consist of: administrative correspondence with test clinic physicians, regarding clinical trial results for various liver extract potencies; administrative correspondence with Eli Lilly and Company, regarding production and distribution of liver extract to test clinics; correspondence with clinics and physicians not associated with the committee, regarding the product's availability and use; and requests for medical advice from patients and physicians. Correspondents include: committee members Walter B. Cannon, William B. Castle, Edwin J. Cohn, and George R. Minot; test clinic physicians Raphael Isaacs (1891-1965) and Cyrus C. Sturgis (born 1891); and Eli Lilly and Company representatives Eli Lilly (1885-1977), and George H. A. Clowes. Records also include: patient records, clinical trial results, and reports submitted to the committee by test clinics during the product's development; and correspondence between George R. Minot and Eli Lilly and Company regarding the company's liver extract production statistics after the product's commercial release.
Records are entirely in English.

Container List

Additional Index Terms

Blood--Diseases.
Clinical trials.
Hematology.
Liver extract.
Pernicious anemia.
Anemia, Pernicious
Clinical Trial
Hematologic Diseases
Hematology
Liver Extracts
Cannon, Walter B. (Walter Bradford), 1871-1945.
Castle, William B. (William Bosworth), 1897-.
Cohn, Edwin J. (Edwin Joseph), 1892-1953.
Minot, George Richards, 1885-1950.
Harvard Medical School. Committee on Pernicious Anemia.
Eli Lilly and Company.

med00176