[OASIS] Harvard University Library
OASIS: Online Archival Search Information System
http://nrs.harvard.edu/urn-3:HMS.Count:med00172View HOLLIS Record   Frames Version
Questions or Comments   Copyright Statement
H MS c214

Isaacs, Raphael, b. 1891. Papers, 1757-1965 (inclusive), 1920-1965 (bulk): Finding Aid.

Center for the History of Medicine (Francis A. Countway Library of Medicine)

[link]


Center for the History of Medicine (Francis A. Countway Library of Medicine)

© President and Fellows of Harvard College


Processing of the Raphael Isaacs papers was funded by the Francis A. Countway Library of Medicine's Charles S. Minot Fund for Hematology.

Descriptive Summary

Call No.: H MS c214
Repository: Center for the History of Medicine (Francis A. Countway Library of Medicine)
Creator: Isaacs, Raphael, b. 1891.
Title: Raphael Isaacs papers,
Date(s): 1757-1965 (inclusive),
Date(s): 1920-1965 (bulk).
Quantity: 8.43 cubic feet ( (8 records center cartons, 1 legal size document box, and 1 oversize box)
Language of materials: Papers are predominantly in English. Occasional correspondence and collected publications are in French, German, Italian, and Latin.
Abstract: The Raphael Isaacs papers, 1757-1965 (inclusive), 1920-1965 (bulk), are a product of Isaacs's research and personal and professional activities as conducted throughout his professional appointments, including: Instructor of Medicine, Harvard Medical School, Boston, Massachusetts; Assistant Physician, Collis P. Huntington Memorial Hospital, Boston; Assistant Director and Assistant Professor of Medicine, Thomas Henry Simpson Memorial Institute for Medical Research, Ann Arbor, Michigan; and Attending Physician in Hematology, Director of the Department of Hematology and the Hematology Research Laboratory, and Senior Attending Physician in Hematology, Michael Reese Hospital, Chicago, Illinois.

Immediate Source of Acquisition:

The Raphael Isaacs Papers were donated to the Harvard Medical Library in the Francis A. Countway Library of Medicine by Roger D. Isaacs in two gifts (1985 and 2002).
  • 2002-058. Donated by Roger D. Isaacs, 2002 August 13.
  • Processing Information:

    Processed by Amber LaFountain, 2012 October.
    Processing staff in the Center for the History of Medicine analyzed, arranged, and described the papers, and created a finding aid to improve access. Items were rehoused and, where necessary, photocopied to acid-free paper. Folder titles were transcribed from the originals when available; titles supplied by the processing staff appear in brackets only on the physical folders.

    Conditions Governing Access:

    Access requires advance notice. Access to personal and patient information is restricted for 80 years from the date of creation. These restrictions appear in Series I, II, III, and IV. Researchers may apply for access to restricted records. Consult Public Services for further information.
    The Papers are stored offsite. Researchers are advised to contact Public Services for more information concerning retrieval of material.

    Conditions Governing Use:

    The Harvard Medical Library does not hold copyright on all the materials in the collection. Requests for permission to publish material from the collection should be directed to Public Services . Researchers who obtain permission to publish from Public Services are responsible for identifying and contacting the persons or organizations that hold copyright.

    Preferred Citation:

    Raphael Isaacs papers, 1757-1965 (inclusive), 1920-1965 (bulk). H MS c214. Harvard Medical Library, Francis A. Countway Library of Medicine, Boston, Mass.

    Related Collections in the Francis A. Countway Library of Medicine, Center for the History of Medicine

    Separations

    Books that came with the collection and constitute a part of Isaacs's professional library were transferred to the Center's Rare Books Collection to be catalogued, October 2012. A complete list of transferred publications is available in the Center's control file for the collection.

    Biographical Notes

    Raphael Isaacs (1891-1965), B.S., 1911, M.A., 1912, M.D., 1918, University of Cincinnati, Ohio, was Instructor of Medicine at Harvard Medical School, Boston, Massachusetts, Assistant Director and Associate Professor of Medicine at the Thomas Henry Simpson Memorial Institute for Medical Research, Ann Arbor, Michigan, and Attending Physician in Hematology at Michael Reese Hospital, Chicago, Illinois. Isaacs worked throughout his career to improve treatments for hematological disorders, including leukemia and pernicious anemia.
    Raphael Isaacs was born in Cincinnati, Ohio in 1891 to Abraham Isaacs (1859-1928) and poet Rachel Isaacs (1861-1929). He attended the University of Cincinnati, where he received his B.S. in 1911, his M.A. in Zoology in 1912, and his M.D. in 1918. Isaacs completed his internship and residency at the Cincinnati General Hospital before serving one year as Instructor in Medicine at the University of Cincinnati. In 1923, he became Instructor in Medicine (1923-1926) at Harvard Medical School and Assistant Physician (1923-1926) at Harvard University's Collis P. Huntington Memorial Hospital, Boston, Massachusetts, where he worked under George R. Minot (1885-1950). Isaacs then moved to Ann Arbor, Michigan in 1927, where he was appointed Assistant Director (1927-1939) and Assistant Professor of Medicine (1927-1939) at the newly opened Thomas Henry Simpson Memorial Institute for Medical Research. In 1940, he left Michigan for the Michael Reese Hospital in Chicago, Illinois, where he subsequently served as Attending Physician in Hematology (1940-1951), Director of the Department of Hematology and the Hematology Research Laboratory (1940-1965), and Senior Attending Physician in Hematology (1952-1965).
    Isaacs's work focused on hematological disorders and their treatments, notably leukemia and pernicious anemia. His research also included studying the effects of radiation on the blood and blood forming tissues. Throughout his career, he collaborated with George R. Minot and Cyrus Sturgis (born 1891) on chronic leukemia and pernicious anemia research. In 1925, he was awarded the Alvarenga Prize of the College of Physicians of Philadelphia, and in 1930 both he and Cyrus Sturgis were awarded the Silver Medal of the American Medical Association for the introduction of powdered hog stomach as an effective treatment of pernicious anemia. Isaacs served as Secretary of the United States Pharmacopoeia Anti-Anemia Products Advisory Board, Diplomat for the American Board of Internal Medicine, Fellow of the American College of Physicians, and Advisory Board Member for the Hematology Research Foundation. His professional affiliations also included the American Society of Clinical Investigation, the Association of American Physicians, the Central Society for Clinical Research, and the International Society of Hematology. Throughout his career, Isaacs also performed clinical trials for numerous pharmaceutical companies. His publications include: Manual of Clinical and Laboratory Technic (1927, 1932) with Hiram Bertram Weiss and Dorothy Stewart Waller; Diagnosis and Treatment of Diseases of the Blood (1930) with Thomas Ordway and Lemuel Whittington Gorham; and Diseases of the Blood (1937) with Cyrus C. Sturgis; as well as over two hundred scientific papers.
    Raphael Isaacs married Agnes Wolfstein (died 1964) in 1923. He had one son, Roger D. Isaacs (born 1925). Isaacs died of a myocardial infarction on 26 October 1965, in Chicago, Illinois.

    Series and Subseries in the Collection

    Scope and Content

    The Raphael Isaacs papers, 1757-1965 (inclusive), 1920-1965 (bulk), are a product of Isaacs's research and personal and professional activities as conducted throughout his professional appointments, including: Instructor of Medicine, Harvard Medical School, Boston, Massachusetts; Assistant Physician, Collis P. Huntington Memorial Hospital, Boston; Assistant Director and Assistant Professor of Medicine, Thomas Henry Simpson Memorial Institute for Medical Research, Ann Arbor, Michigan; and Attending Physician in Hematology, Director of the Department of Hematology and the Hematology Research Laboratory, and Senior Attending Physician in Hematology, Michael Reese Hospital, Chicago, Illinois.
    The papers are arranged in five series: I. Clinical, Research, and Publishing Files (1855-1899, 1910-1965, undated); II. Correspondence (1915-1965, undated); III. Professional Activities and Service Records (1922-1964, undated); IV. Professional Appointments Records (1923-1953, undated); and V. Biographical Resource Files (1757-1850, 1910-1951, undated). There is substantial topical overlap across series due to the collection's original arrangement. Series content is as follows:
    Papers are predominantly in English. Occasional correspondence and collected publications are in French, German, Italian, and Latin.

    Container List

    Additional Index Terms

    Blood--Diseases.
    Erythrocytes.
    Harvard Medical School--Faculty.
    Hematology.
    Leukemia.
    Pernicious anemia.
    Anemia, Pernicious
    Erythrocytes
    Hematologic Diseases
    Hematology
    Leukemia
    Drawings (visual works).
    Negatives (photographic).
    Notebooks.
    Photographs.
    Hematologists.
    Castle, William B. (William Bosworth), 1897-
    Christian, Henry A. (Henry Asbury), 1876-1951.
    Daland, Geneva A.
    Downey, Hal, 1877-
    Isaacs, Raphael, b. 1891.
    Minot, George Richards, 1885-1950.
    Abbott Laboratories.
    Burroughs Wellcome and Company.
    Eli Lilly and Company.
    Huntington Memorial Hospital.
    Lederle Laboratories.
    Michael Reese Hospital.
    Thomas Henry Simpson Memorial Institute for Medical Research.
    Upjohn Company.

    med00172